BR+NAD® Is More Than a Treatment — It’s a Standard of Care.

Developed in 2001 by Paula Norris Mestayer and Dr. Richard Mestayer III, BR+NAD® is the original NAD+ IV protocol, developed to support mental health recovery, addiction treatment, neuroprotection, and overall brain restoration.

For more than two decades, BR+NAD® has represented a structured, professionally administered approach to NAD+ therapy—grounded in clinical experience, individualized care, and ongoing research.

Meet the BR+NAD® Family

For more than two decades, our team has advanced the field of NAD+ therapy through clinical care, physician education, and scientific research. Today, that mission continues through three organizations, each with a distinct role:

Springfield Wellness Center — Our original clinic, providing direct-to-patient BR+NAD® therapy and carrying forward the clinical legacy established in 2001.

BR+MD Consultants — Our professional education and product branch, originally created to teach the BR+NAD® protocol to physicians and healthcare providers.

NAD Research, Inc. — Our nonprofit research organization, dedicated to advancing the scientific understanding of NAD+ and its potential applications in addiction recovery, neurodegenerative disease, mental health, and more.

Each branch plays a vital role. Together, they reflect one unified goal: To make NAD+ therapy accessible, trusted, and grounded in science.

What Sets BR+NAD® Apart?

NAD+ therapy has grown dramatically in popularity. But not all NAD+ therapy is the same. BR+NAD® was developed specifically for clinical application and is distinguished by its emphasis on medical oversight, structured protocols, research, and product quality.

Medical Oversight – BR+NAD® protocols are designed for real clinical settings—not generic wellness menus. Treatment is individualized, professionally administered, and guided by established clinical parameters.

Precise Protocols – Dosing, pacing, treatment duration, and formulation are important components of NAD+ therapy. The BR+NAD® approach reflects more than two decades of clinical experience and ongoing research.

Research & Clinical Experience – The BR+NAD® legacy is supported by decades of clinical experience and research conducted through NAD Research, Inc., exploring NAD+’s potential applications in addiction recovery, mental health, neurodegenerative disease, and other areas of health.

High-Purity Formulations – BR+NAD® extends beyond IV therapy into advanced NAD+ delivery technologies, including the proprietary nanoNAD+ Power Spray.

Legacy & Experience – Trusted Nationwide – For more than two decades, the BR+NAD® protocol has been used by trained providers across the country.

Whether receiving treatment at Springfield Wellness Center or through an affiliated BR+MD® provider, patients can expect an approach rooted in professional training, established protocols, and the clinical legacy of BR+NAD®.

No shortcuts. No guesswork. Just science, experience, and a commitment to better care.

The Science Behind BR+NAD®

Interest in NAD+ has grown significantly throughout the medical and scientific communities. Through NAD Research, Inc., ongoing research continues to explore the role of NAD+ in addiction recovery, brain health, neurodegenerative disease, mental health, and other areas of human health.

Explore the research behind BR+NAD® →

One Legacy. One Mission.

BR+NAD® is a collaborative mission shared by Springfield Wellness Center, BR+MD Consultants, and NAD Research, Inc. Together, we continue to advance NAD+ therapy through clinical care, professional education, scientific research, and trusted product development.

BR+NAD® — Where experience, science, and innovation come together.